The Best Mp3 Audio Books To Improve Your Mind
By KhmengWat.com
It's indeed incredible that not many people pay a great deal of attention to what gets into their minds. If your mind is positive and creative, you can become all you ever dream of becoming. Most Read more...
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Wireless Ecg
By KhmengWat.com
A Holter monitor is an ECG recording done over a period of 24 or more hours. Electrodes are attached to the patient's chest and connected to a Digital Holter Recorder by lead wires. The patient goes about his/her usual daily activities (except for activities such as taking a shower, swimming, or any activity causing an excessive amount of sweating which would cause the electrodes to become loose or fall off) during this procedure. There are 2 types of Holter monitoring:
Continuous recording - the ECG is recorded continuously during the entire testing period.
Event monitor, or loop recording - the ECG is recorded only when the patient starts the recording on the Event Recorder or Loop Recorder, when symptoms are felt.
Holter monitoring may be done when arrhythmia is suspected but not seen on a resting or signal-average ECG, since arrhythmias may be transient in nature and not seen during the shorter recording
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Celiac disease in patients with type-1 diabetes mellitus screened by tissue transglutaminase antibodies in northwest of iran
Conclusion:&lt;/b&gt; This study showed higher prevalence of CD in patients with T1DM than in general population of northwest Iran and the data lend support to recommend regular screening for CD in all patients with T1DM. (Source: International Journal of Diabetes in Developing Countries)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
News from the american chemical society nov. 12, 2008
A faster test for the food protein that triggers celiac disease Researchers in Spain and the United Kingdom are reporting development of a faster test for identifying the food protein that triggers celiac disease, a difficult-to-diagnose digestive disease involving the inability to digest protein called gluten that occurs in wheat, oats, rye, and barley. (Source: Nutrition/Agriculture News From Medical News Today)
Celiac disease: faster gluten test
A new test can detect the gluten protein gliadin in food in 90 minutes versus the current method that takes 8 hours. WebMD Health News (Source: Medscape Medical News Headlines)
Tissue transglutaminase antibodies in individuals with celiac disease bind to thyroid follicles and extracellular matrix and may contribute to thyroid dysfunction
Thyroid Nov 2008, Vol. 18, No. 11: 1171-1178.
Background: Individuals with active celiac disease (CD+) have an increased incidence of thyroid dysfunction, which improves on a gluten-free diet (CD?). We investigated whether tissue transglutaminase-2 IgA antibodies (anti-TGase II) present in sera of ... (Source: Thyroid)
Celiac disease: faster gluten test
Celiac Disease: Faster Gluten Test (Source: eMedicineHealth.com)
Dining guide helps those with gluten problems
A brush with bread can have grave consequences for Janet McKenzie Prince. Prince?s body can?t tolerate some of the proteins in gluten, found in wheat, rye and barley. She's one of an estimated 2 million Americans who can accidentally eat a crouton and end up with digestive issues and problems absorbing nutrients - an autoimmune disorder called celiac disease. (Source: Knoxville News Sentinel: Health and fitness)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Celiac disease: faster gluten test
Scientists have developed a new test that could speed up identification of gluten, a trigger for people with celiac disease. (Source: WebMD Health)
Celiac disease and myointimal proliferation: a possible correlation?
Case Rep Gastroenterol 2008;2:398-404 (DOI:10.1159/000163522) (Source: Karger Publishers)
A faster test for the food protein that triggers celiac disease - analytical chemistry journal
Researchers in Spain and the United Kingdom are reporting development of a faster test for identifying the food protein that triggers celiac disease, a difficult-to-diagnose digestive disease involving the inability to digest protein called gluten that occurs in wheat, oats, rye, and barley. The finding could help millions of people avoid diarrhea, bloating, and other symptoms that occur when they unknowingly eat foods containing gluten. (Source: Crohn's News From Medical News Today)
Spontaneous isolated dissection of the celiac trunk with rupture of the proximal splenic artery: a case report.
We present a case with synchronous rupture of the splenic artery causing massive bleeding and demanding urgent surgery. To our knowledge, only 24 previous cases are reported in the literature. REPORT: The patient was a 56-year-old male smoker with no previous medical history who was treated surgically with exposure of the suprarenal aorta through left-sided medial visceral rotation and isolation of the celiac artery. The origin of the bleeding was identified as a longitudinal rupture of the splenic artery just distal to the hepatic artery. The artery was ligated and splenectomy was performed because of splenic infarction. The hepatic artery was patent and no reconstruction was needed. The postoperative course was uneventful, treatment with antiplatelets and antihypertensive drugs was initi...
Expression of cyclin a in intestinal biopsies from children with celiac disease.
In conclusion, these studies enabled us visualized pattern of distribution of cyclin A but let us also to presume that observed decrease of expression and its distribution might function as additional factor which could be taken under consideration to establish terminal diagnosis. We are aware of the fact that these are very first observations and that this subject needs to be further investigated with the use of additional methods and samples. Key words: celiac disease, cyclin A, immunogold, immunohistochemistry.
PMID: 18999879 [PubMed - in process] (Source: Neoplasma)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Intraepithelial lymphocytes in duodenum from brazilian adolescents with type 1 diabetes. influence of helicobacter pylori
Conclusions: The density of IELs in the distal duodenum of diabetic adolescents did not differ from that observed in older children and adolescents without this autoimmune disease. H.pylori infection, which is frequent among adolescents from developing countries, did not modify lymphocyte density in the distal duodenum in the absence of lymphocytic gastritis. (Source: Pediatric Diabetes)
Effects of carbon monoxide on trout and lamprey vessels.
Effects of Carbon Monoxide on Trout and Lamprey Vessels.
Am J Physiol Regul Integr Comp Physiol. 2008 Nov 12;
Authors: Dombkowski RA, Whitfield NL, Motterlini R, Gao Y, Olson KR
Carbon monoxide (CO) is endogenously produced by hemoxygenase (HO) and is involved in vascular, neural, and inflammatory responses in mammals. However, the biological activities of CO in non-mammalian vertebrates is unknown. To this extent, we utilized smooth muscle myography to investigate the effects of exogenously applied CO (delivered via a water-soluble CO-releasing molecule, CORM-3) on isolated lamprey (Petromyzon marinus) dorsal aortas and examined its mechanisms of action on trout (Oncorhynchus mykiss) efferent branchial (EBA) and celiacomesenteric (CMA) arteries. CORM-3 dose-dependently relaxed...
A common barrier defect for celiac disease and ulcerative colitis.
A Common Barrier Defect for Celiac Disease and Ulcerative Colitis.
Gastroenterology. 2008 Nov 12;
Authors: Mannon PJ
PMID: 19013169 [PubMed - as supplied by publisher] (Source: Gastroenterology)
Local accumulation and activation of regulatory foxp3+ cd4 tr cells accompanies the appearance of activated cd8 t cells in the liver
Conclusion: Although it contains only a small population of quiescent Foxp3+ CD4 TR cells, the liver can rapidly mobilize and/or recruit this T cell control in response to the intrahepatic appearance of peripherally or locally generated CD8 T blasts. (HEPATOLOGY 2008.) (Source: Hepatology)
Analysis of genomic instability in adult-onset celiac disease patients by microsatellite instability and loss of heterozygosis.
Page: 1159DOI: 10.1097/MEG.0b013e3283094ee9Authors: Fundia, Ariela F. a; Cottliar, Alejandra S. a; La Motta, Graciela b; Crivelli, Adriana b; Gomez, Juan Carlos b; Slavutsky, Irma R. a; Larripa, Irene B. a (Source: European Journal of Gastroenterology & Hepatology)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Prevalence of celiac disease among patients with behcet?s disease in iran
Conclusion Our findings didn?t support any association between celiac disease and Behcet?s disease in Iranian patients compared to the
general population of Iran.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-008-0548-8Authors
Farhad Zamani, Iran University of Medical Sciences Gastrointestinal and Liver Disease Research Center Tehran IranFarhad Shahram, Shariati Hospital, Tehran University of Medical Sciences Rheumatology Research Center Tehran IranRamin Shakeri, Shariati Hospital, Tehran University of Medical Sciences Digestive Disease Research Center North Kargar Ave. Tehran 14117-13135 IranHabib Zayyeni, Shariati Hospital, Tehran University of Medical Sciences Rheumatology Research Center Tehran IranFereydoun Davatchi, Shariati Hospital, Tehran Univer...
Serum zinc in small children with coeliac disease
Conclusion: Serum zinc concentration is decreased in untreated coeliac children with enteropathy and normalizes on gluten-free diet. A low serum zinc value in a child being investigated for possible CD on clinical grounds can thus be used as a complementary marker for enteropathy indicating further investigation with small bowel biopsy. The hypothetical role of zinc in the pathogenesis of CD is discussed. (Source: Acta Paediatrica)
Histological abnormalities of the small bowel mucosa in cirrhosis and portal hypertension.
CONCLUSION: This study provides evidence for the lack of villus atrophy in patients with cirrhosis and portal hypertension, and supports the continuous reliance on the Marsh criteria when the diagnosis of coeliac disease is to be made in the presence of cirrhosis.
PMID: 19009654 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Coeliac disease
(Source: Nutrition and Dietetics)
Reduced diversity and increased virulence-gene carriage in intestinal enterobacteria of children with coeliac disease
Conclusion:
This study has demonstrated that virulence features of the enteric microbiota are linked to coeliac disease. (Source: BMC Gastroenterology)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Leading dietitian scoops national recognition, epsom general hospital, england
A leading dietitian based at Epsom General Hospital has been crowned 'Dietitian of the Year' by a national charity. Kristina Zaremba who has been working in the field for the past 28 years, said she was delighted with the accolade, awarded to her by Coeliac UK. The charity supports people with coeliac disease - a condition that affects one in 100 people across the UK. (Source: Nutrition/Agriculture News From Medical News Today)
Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients
Conclusions:
The intestinal microbiota of CD patients could contribute to the Th1 pro-inflammatory milieu characteristic of the disease, while B. longum ES1 and B. bifidum ES2 could reverse these deleterious effects. These findings hold future perspectives of interest in CD therapy. (Source: BioMed Central)
Increased superoxide levels in ganglia and sympathoexcitation are involved in sarafotoxin 6c-induced hypertension
Endothelin (ET) type B receptors (ETBR) are expressed in multiple tissues and perform different functions depending on their location. ETBR mediate endothelium-dependent vasodilation, clearance of circulating ET, and diuretic effects; all of these should produce a fall in arterial blood pressure. However, we recently showed that chronic activation of ETBR in rats with the selective agonist sarafotoxin 6c (S6c) causes sustained hypertension. We have proposed that one mechanism of this effect is constriction of capacitance vessels. The current study was performed to determine whether S6c hypertension is caused by increased generation of reactive oxygen species (ROS) and/or activation of the sympathetic nervous system. The model used was continuous 5-day infusion of S6c into male Sprague-Dawl...
Ige-mediated cereal allergy and latent celiac disease.
IgE-mediated cereal allergy and latent celiac disease.
J Investig Allergol Clin Immunol. 2008;18(5):412-4
Authors: Torres JA, Sastre J, de las Heras M, Cuesta J, Lombardero M, Ledesma A
PMID: 18973112 [PubMed - in process] (Source: Journal of Investigational Allergology & Clinical Immunology)
Hemosuccus pancreaticus in a patient with celiac trunk aneurysm.
Authors: Fazel I, Asle Soleimani H, Fallah S, Babaei M, Sedighi N, Marashi A, Beniaz F, Malekzadeh R
Celiac artery aneurysm associated with hemosuccus pancreaticus is extremely rare. We herein present a 67-year-old man with a large celiac artery aneurysm presenting with intermittent massive gastrointestinal bleeding due to connection of aneurysm with a blood-filled pancreatic duct who was successfully operated. To the best of our knowledge, this is the first report of a case of hemosuccus pancreaticus due to celiac artery trunk aneurysm.
PMID: 18976038 [PubMed - in process] (Source: Archives of Iranian Medicine)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Regulatory t-cell function is impaired in celiac disease
Abstract Celiac disease (CD) is characterized by intolerance to gluten and high risk of developing autoimmune phenomena. Possible defects
in immune tolerance could have a role in the pathogenesis of the disease. As regulatory T-cells (Tregs) are the main population
involved in maintaining peripheral tolerance, we investigated the number of these cells in celiac patients as compared with
healthy donors. Moreover, we analyzed the suppressive function of CD4+CD25+ T-cells from celiac disease patients and controls
on autologous responder T-cells (CD4+CD25?). The percentage of CD4+CD25+FOXP3+ cells was not different in celiacs and in healthy
controls, and among positive cells the level of expression of the two regulatory markers was comparable. However, the suppressor
activit...
A blinded pilot comparison of capsule endoscopy and small bowel histology in unresponsive celiac disease
This study compares video capsule endoscopy (VCE) with histological specimens of proximal small bowel in patients with celiac
disease who have failed to respond to a gluten-free diet. Patients with nonresponsive celiac disease underwent capsule endoscopy,
and concordance between endoscopy and histology was then calculated using the kappa statistic. In 19 patients, endoscopy videos
were reported as normal in ten (53%) case, as having mild changes in three (16%) cases, and as having moderate-severe changes
in six (31%) cases. Two (11%) had acute ulcers. No small bowel tumors were seen. Endoscopy demonstrated concordance with histological
changes in 14 of the 18 patients with histology available (78% concordance). The kappa statistic suggested a substantial degree
of concordance between...
Celiac axis and superior mesenteric artery: danger zone for left nephrectomy
We report two cases of iatrogenic occlusion of the superior mesenteric artery (SMA) and celiac axis (CA) during left nephrectomy. A patient with a urothelial carcinoma (open surgery) and one with coralliform calculi (laparoscopy) experienced injury to ... (Source: Journal of Endourology)
Alvine pharmaceuticals reports positive results with alv003 in phase 1 trial of therapy in development for celiac disease
Alvine Pharmaceuticals, Inc., today announced proof of concept in a Phase 1 Trial of ALV003, an oral protease therapy in development to detoxify gluten, intended for use by patients with celiac disease. The trial results confirmed that single doses of up to 1,800 mg of ALV003 were safe and tolerable in healthy volunteers. (Source: Health News from Medical News Today)
Noninvasive evaluation of the celiac trunk and superior mesenteric artery with multislice ct in patients with chronic mesenteric ischaemia
Conclusions MSCT angiography can play a major role in the detection of stenosis of the abdominal arteries in patients with suspected CMI.
Content Type Journal ArticleCategory Abdominal Radiology/Radiologia AddominaleDOI 10.1007/s11547-008-0330-1Authors
F. Cademartiri, Azienda Ospedaliero-Universitaria Dipartimento di Diagnostica per Immagine Parma ItalyA. Palumbo, Azienda Ospedaliero-Universitaria Dipartimento di Diagnostica per Immagine Parma ItalyE. Maffei, Azienda Ospedaliero-Universitaria Dipartimento di Diagnostica per Immagine Parma ItalyC. Martini, Azienda Ospedaliero-Universitaria Dipartimento di Diagnostica per Immagine Parma ItalyR. Malagò, Università degli Studi Dipartimento di Radiologia Verona ItalyM. Belgrano, Università degli Studi Dipartimento di Radi...<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Peripancreatic lymphatic invasion by pancreatic carcinoma: evaluation with multi-detector row ct
Abstract Peripancreatic lymphatic networks are frequently involved in pancreatobiliary carcinoma, affecting the prognosis. However,
little attention has been paid to CT imaging of normal and pathological conditions of peripancreatic lymphatic networks. We
evaluated multi-detector row CT (MDCT) images of peripancreatic lymphatic networks invaded by pancreatic carcinoma and compared
them with those of normal peripancreatic lymphatic networks using imaging reconstruction every 1 mm with a multiplanar reformation
technique. Apart from the region around the pancreatic body and tail, normal peripancreatic lymphatic networks were detected
as ?linear structures? on MDCT. However, peripancreatic lymphatic invasion by pancreatic carcinoma was frequently identified
as ?ret...
Pancreatic autoantibodies are associated with reactivity to microbial antibodies, penetrating disease behavior, perianal disease, and extraintestinal manifestations, but not with nod2/card15 or tlr4 genotype in a hungarian ibd cohort
Conclusions: PAB autoantibodies in combination with ASCA or anti-glycan antibodies increase the sensitivity for detecting CD, especially isolated colonic CD. Antibody response to PAB was associated with complicated disease phenotype and extraintestinal manifestations in this Eastern European IBD cohort.(Inflamm Bowel Dis 2008) (Source: Inflammatory Bowel Diseases)
Alvine pharmaceuticals reports positive results with alv003 in phase 1 trial of therapy in development for celiac disease
SAN CARLOS, Calif.--(BUSINESS WIRE)--Oct. 29, 2008 - Alvine Pharmaceuticals, Inc., today announced proof of concept in a Phase 1 Trial of ALV003, an oral protease therapy in development to detoxify gluten, intended for use by patients with celiac... (Source: Drugs.com - Clinical Trials)
Influence of previously ingested wheat on fasting breath hydrogen in celiac patients
Abstract The excretion of hydrogen in breath commonly persists, despite an overnight fast. Although the elevation of hydrogen concentration
above the fasting value after the administration of a test sugar is evidence of malabsorption, the level of the fasting value
itself in untreated celiac patients is unknown. Therefore, we studied the fasting breath hydrogen (FBH2) concentration in 40 healthy controls, 35 subjects with functional bowel disorders, and 30 patients of untreated celiac disease
with and without bread or wheat diet one day before the test. The fasting level of hydrogen concentration in untreated celiac
patients (28.7 ± 19.5 ppm) was significantly higher than those in healthy volunteers (9.5 ± 3.4 ppm) and subjects with functional...
Effects of gastric distension and feeding on cardiovascular variables in the shorthorn sculpin (myoxocephalus scorpius).
In conclusion, the response to mechanical distension of the stomach is similar to what we have described in rainbow trout and the postprandial gastrointestinal hyperemia is most likely chemically induced. Key words: postprandial blood flow, coeliaco-mesenteric artery, mechanical stimuli, shunting of blood.
PMID: 18971353 [PubMed - as supplied by publisher] (Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
[neurological and psychiatric aspects of some gastrointestinal diseases.]
[Neurological and psychiatric aspects of some gastrointestinal diseases.]
Orv Hetil. 2008 Nov 2;149(44):2079-86
Authors: Aszalós Z
The gastrointestinal tract is controlled by the independent enteric nervous system. It is also closely connected to the central nervous system, and bi-directional communication exists between them. The communication involves neural pathways as well as immune and endocrine mechanisms. The brain-gut axis plays a prominent role in the modulation of gut functions. Signals from different sources (e.g. sound, sight, smell, somatic and visceral sensations, pain) reach the brain. These inputs are modified by memory, cognition and affective mechanisms and integrated within the neural circuits of the central nervous system, spinal cord, autonomic and ent...
Living well with celiac disease?.
Page: 544DOI: 10.1097/MPG.0b013e31817fcb7fAuthors: Hornell, Agneta (Source: Journal of Pediatric Gastroenterology and Nutrition)
Quality of life in adolescents with treated coeliac disease: influence of compliance and age at diagnosis.
Page: 555DOI: 10.1097/MPG.0b013e31817fcb56Authors: Wagner, Gudrun *; Berger, Gabriele *; Sinnreich, Ursula *; Grylli, Vasileia *; Schober, Edith +; Huber, Wolf-Dietrich +; Karwautz, Andreas * (Source: Journal of Pediatric Gastroenterology and Nutrition)
Comparison of a novel whole blood transglutaminase-based elisa with a whole blood rapid antibody test and established conventional serological celiac disease assays.
Page: 562DOI: 10.1097/MPG.0b013e3181615cdeAuthors: Raivio, Tiina *; Korponay-Szabo, Ilma R ***; Paajanen, Tuula *; Ashorn, Merja *,[S]; Iltanen, Sari *; Collin, Pekka +,++; Laurila, Kaija *; Nemes, Eva **; Kovacs, Judit B ++; Carrard, Geraldine [P]; Saramaki, Mika ||; Maki, Markku *,[S]; Kaukinen, Katri *,+,++ (Source: Journal of Pediatric Gastroenterology and Nutrition)
Lymphocytic gastritis and celiac disease in indian children: evidence of a positive relation.
Page: 568DOI: 10.1097/MPG.0b013e31816232a7Authors: Prasad, Kaushal K *; Thapa, Babu R +; Lal, Sadhna +; Sharma, Arun K ++; Nain, Chander K ++; Singh, Kartar ++ (Source: Journal of Pediatric Gastroenterology and Nutrition)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Duodenal bulb biopsies in celiac disease: a multicenter study.
Page: 618DOI: 10.1097/MPG.0b013e3181677d6eAuthors: Bonamico, Margherita *; Thanasi, Enina *; Mariani, Paolo *; Nenna, Raffaella *; Luparia, Rita Pia Lara *; Barbera, Cristiana +; Morra, Isabella +; Lerro, Pietro +; Guariso, Graziella ++; De Giacomo, Costantino [S]; Scotta, Serenella [P]; Pontone, Stefano ||; Carpino, Francesco **; Magliocca, Fabio Massimo **; and the Societa Italiana di Gastroenterologica, Epatologia, e Nutrizione Pediatrica (Source: Journal of Pediatric Gastroenterology and Nutrition)
Gluten measurement and its relationship to food toxicity for celiac disease patients
The gluten analysis of foods has long had limitations, which have precluded food standards authorities from issuing standards for gluten-free foods based on final gluten content. The Codex Alimentarius and the Food and Drug Administration have recently taken steps towards such standards in which they favour the R5-enzyme-linked immunosorbent assay for gluten analysis. If this method is to be widely employed, its limitations should be recognised. Above all, it should be noted the ability of the R5-enzyme-linked immunosorbent assay, and other methods, to measure gluten's toxicity toward celiac disease patients is not validated clinically. Gluten is a complex mixture of proteins and its toxicity is not fully understood. Analytical methods are a valuable tool in the definition of gluten-free f...
Infectious associations of celiac disease.
Infectious associations of Celiac disease.
Autoimmun Rev. 2008 Oct 28;
Authors: Plot L, Amital H
Infectious agents have been implicated in the pathogenesis of many autoimmune diseases. Celiac disease (CD) is an autoimmune disorder affecting patients with a specific genetic predisposition (HLA-DQ2, HLA-DQ8) who are exposed to gluten, the major storage protein of wheat and similar grains. An environmental factor, such as an infectious agent, is thought to precipitate the disease via various pathogenic mechanisms, such as molecular mimicry, resulting in modulation of the host's immune tolerance. There is evidence that CD is related to perinatal infections, and that maternal-milk may have a protective role. Observations imply that there is a relationship between viral infections su...
[original articles] investigation of molecular markers in the diagnosis of refractory coeliac disease in a large patient cohort
Conclusions:
This study supports the use of phenotypic and T cell clonality investigations in identifying patients with true rCD. (Source: Journal of Clinical Pathology)
Pediatric and adolescent medicinefrontiers in celiac disease
(Source: Acta Paediatrica)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Get support for celiac disease, gluten free recipes, and moderated discussions by
joining the active community at <a href="http://sensibleceliac.com">The Sensible Celiac</a>.</p>
Efficacy of endoscopic ultrasound (eus) guided celiac plexus block (cpb) for managing abdominal pain associated with chronic pancreatitis (cp): a meta-analysis.
Page: 477DOI: 10.1097/01.MPA.0000335485.84721.6bAuthors: Kaufman, M. S. 1; Singh, G. 1; Das, S. 2; Erber, J. A. 1; Micames, C. 3; Cristescu, B. 1; Gress, F. G. 1 (Source: Pancreas)
Efficacy of endoscopic ultrasound (eus) guided celiac plexus neurolysis (cpn) for managing abdominal pain associated with pancreatic cancer: a meta-analysis.
Page: 496DOI: 10.1097/01.MPA.0000335391.53014.98Authors: Singh, G. 1; Kaufman, M. 1; Das, S. 2; Gress, F. 1 (Source: Pancreas)
Protective effects of glycyrrhizin in a gut hypoxia (ischemia)-reoxygenation (reperfusion) model
Conclusions This study demonstrates that glycyrrhizin exerts multiple protective effects in splanchnic artery occlusion?reperfusion shock.
Content Type Journal ArticleCategory OriginalDOI 10.1007/s00134-008-1334-yAuthors
Rosanna Di Paola, IRCCS Centro Neurolesi ?Bonino-Pulejo? Messina ItalyMarta Menegazzi, University of Verona Biochemistry Division, Department of Neuroscience and Vision Verona ItalyEmanuela Mazzon, IRCCS Centro Neurolesi ?Bonino-Pulejo? Messina ItalyTiziana Genovese, IRCCS Centro Neurolesi ?Bonino-Pulejo? Messina ItalyConcetta Crisafulli, Policlinico Universitario Department of Clinical and Experimental Medicine and Pharmacology, Torre Biologica 98123 Messina ItalyMartina Dal Bosco, IRCCS Centro Neurolesi ?Bonino-Pulejo? Messina ItalyZ...
Plasma exchange for anti-gad associated non paraneoplastic limbic encephalitis.
Plasma exchange for anti-GAD associated non paraneoplastic limbic encephalitis.
Transfus Apher Sci. 2008 Oct 25;
Authors: Mazzi G, Roia DD, Cruciatti B, Matà S, Catapano R
Limbic encephalitis (LE) is a neurological syndrome usually presenting in a paraneoplastic form. Recently many cases were reported with no concurring neoplasia, presenting with specific antibodies for voltage-gated potassium channel or for neuronal membrane antigens. Anti-glutamic acid decarboxylase (GAD) antibodies act against GABAergic receptors of the central nervous system. These antibodies were found in coeliac disease serum and in neurologic patients. We are reporting a case of a 21-year-old coeliac woman manifesting complex multiple-daily partial drug-resistant seizures for 7 years. The diagnosis ...
times of the resting or signal-averaged ECG.
Also called: 24 hour ECG
What is an ambulatory blood pressure monitor or holter blood pressure monitor?
It is a small device, about the size of a portable radio. Typically it is worn on a belt. The blood pressure cuff on the monitor can be worn under your clothes without anyone seeing it.
This machine lets your doctor find out what your blood pressure was every 20 to 30 minutes of a day. The information collected by this machine can help you and your doctor see if your blood pressure treatment is working.
Your doctor may want you to use an ambulatory blood pressure monitor for one or more of the following reasons:
If you have "borderline" high blood pressure
If you and your doctor can't keep your blood pressure under control
If you have blood pressure problems caused by your other medicines
If you have fainting spells
The monitor may help your doctor find out if you are a person who only has high blood pressure when you are at the doctor's office, called "white-coat hypertension." If you have this kind of hypertension, you may not need to take medicine.
What happens when I wear the monitor?
The small blood pressure cuff that is connected to the monitor will automatically check your blood pressure about every 30 minutes, even while you are sleeping. You also will be asked to keep a diary of your day's activities, so your doctor will know when you were active and when you were resting. Some people feel a little sore from the frequent pressure checks.
After 24 hours of monitoring, you will take the machine and your diary to the doctor's office. The blood pressure information is transferred from the monitor to a computer. Your doctor will review the information with you and decide if your treatment program is working or if you need to make changes to it.
If more advanced diagnostic testing is needed the patient is often referred for imaging tests.
Examples of imaging tests are MUGA and Echo. For these systems to take the image at the right phase of the cardiac cycle an ECG Trigger is used.
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The University of Alabama at Birmingham (UAB) Center for Education and Research on Therapeutics (CERTs) has won a $2.2 million federal grant to study the risks and benefits of a newer class of medicines called biologics. These are genetically engineered therapies that target the immune system of patients who have rheumatoid arthritis, Crohn's disease, psoriasis and other autoimmune disorders. (Source: Health News from Medical News Today)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Crohn's disease patients at risk of significant diagnostic radiation exposure
Recent findings published in the November issue of the journal Gut suggest that there are identifiable subsets of patients with Crohn's disease who are at risk of exposure to high levels of diagnostic radiation. Reuters Health Information (Source: Medscape Radiology Headlines)
Prometheus presents new clinical insights into diagnosis of crohn's disease in children from analysis of prometheus(r) ibd serology 7 test results
Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, announced new findings regarding the correlation between serologic markers and the diagnostic predictions of children with Crohn's disease following an analysis of PROMETHEUS(R) IBD Serology 7 test results. (Source: Crohn's News From Medical News Today)
Pfizer announces plan for stem cell unit
FROM IBD NEWS SERVICES (Source: Investor's Business Daily: HEALTH)
Crohn's disease patients at risk of significant diagnostic radiation exposure
NEW YORK (Reuters Health), Nov 18 - Recent findings published in the November issue of the journal Gut suggest that there are identifiable subsets of patients with Crohn's disease who are at risk of exposure to high levels of diagnostic radiation. (Source: AuntMinnie.com Headlines)
Crohn's disease surgeries make steady advances
(New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College) Thousands of Americans suffering from the chronic inflammatory bowel condition known as Crohn's disease are leading longer, healthier lives due to innovative new surgeries, according to experts at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. (Source: EurekAlert! - Cancer)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Musculoskeletal center wins $2.2 million for drug safety
(University of Alabama at Birmingham) The UAB Center for Education and Research on Therapeutics has won a $2.2 million federal grant to study the risks and benefits of a class of drugs called "biologics." These are agents genetically engineered to target the immune system of patients with rheumatoid arthritis, Crohn's disease, psoriasis and other autoimmune disorders. The grant will allow the UAB center to pinpoint which biologics have safety concerns and which work best for specific groups of patients. (Source: EurekAlert! - Biology)
[immunology] thymus leukemia antigen controls intraepithelial lymphocyte function and inflammatory bowel disease
Intestinal intraepithelial lymphocytes (IEL) bear a partially activated phenotype that permits them to rapidly respond to antigenic insults. However, this... (Source: Proceedings of the National Academy of Sciences)
The world in medicine: gut bacteria and crohn disease
(Source: JAMA)
Downregulation of cpi-17 contributes to dysfunctional motility in chronic intestinal inflammation model mice and ulcerative colitis patients
Conclusions CPI-17 downregulation might contribute to the decreased motor function in chronic inflammatory bowel diseases.
Content Type Journal ArticleCategory Alimmentary TractDOI 10.1007/s00535-008-2241-2Authors
Takashi Ohama, The University of Tokyo Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences 1-1-1 Yayoi, Bunkyo-ku Tokyo 113-8657 JapanMasatoshi Hori, The University of Tokyo Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences 1-1-1 Yayoi, Bunkyo-ku Tokyo 113-8657 JapanMasahiko Fujisawa, The University of Tokyo Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences 1-1-1 Yayoi, Bunkyo-ku Tokyo 113-8657 JapanMasaharu Kiyosue, The University of Tokyo Departmen...
Escherichia coli type 1 pili trigger late il-8 production by neutrophil-like differentiated plb-985 cells through a src family kinase- and mapk-dependent mechanism.
Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism.
J Leukoc Biol. 2008 Nov 17;
Authors: Semiramoth N, Gleizes A, Turbica I, Sandre C, Gorges R, Kansau I, Servin A, Chollet-Martin S
The innate immune response to enteropathogenic bacteria includes chemokine-induced polymorphonuclear neutrophil (PMN) migration across mucosal epithelia leading to bacterial clearance and resolution of infection. Among these bacteria, diffusely adherent Escherichia coli expressing Afa/Dr fimbriae (Afa/Dr DAEC), causing childhood diarrhea, can promote IL-8-dependent PMN transmigration across cultured intestinal epithelial cell monolayers via MAPK pathway activation. However, interactions b...<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Crohn's disease researchers in plea for study volunteers
PATIENTS with Crohn's disease are being invited to take part in pioneering research that may find the first preventative medicine for their condition. (Source: Scotsman.com News - Health)
Crohn's disease in an african-american population.
Page: 389DOI: 10.1097/MAJ.0b013e31816a5c06Authors: JACKSON, JAMES F. III MD; DHERE, TANVI MD; REPAKA, APARNA MD; SHAUKAT, AASMA MD, MPH; SITARAMAN, SHANTHI MD, PhD (Source: The American Journal of the Medical Sciences)
Predictive value of serologic markers in a population-based norwegian cohort with inflammatory bowel disease
Conclusions: The prevalence of ASCA in CD and pANCA in UC appears markedly lower than in referral-based populations. Even with the low prevalence, our study gives further support to the role of ASCA and pANCA as markers for distinct phenotype and outcome of disease.(Inflamm Bowel Dis 2008) (Source: Inflammatory Bowel Diseases)
Once daily salofalk granules now available in 1.5g sachet for ulcerative colitis
Dr Falk Pharma has today launched Salofalk granules in a new 1.5g sachet. Treatment of active ulcerative colitis once daily is now even easier with the new sachet as it offers patients simpler dosing of one or two sachets a day. A recent study, published in Gut, showed that 80% of patients preferred once daily dosing to three times daily, both of which are efficacious and safe. (Source: Health News from Medical News Today)
Adalimumab may reduce health-care costs for crohn's disease patients
Additional study shows further research needed on 5-ASA's chemopreventative role in ulcerative colitis Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD). IBD occurs most frequently in people in their late teens and twenties. There have been cases in children as young as two years old and in older adults in their seventies and eighties; men and women have an equal chance of getting the disease. (Source: Crohn's News From Medical News Today)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
A faster test for the food protein that triggers celiac disease - analytical chemistry journal
Researchers in Spain and the United Kingdom are reporting development of a faster test for identifying the food protein that triggers celiac disease, a difficult-to-diagnose digestive disease involving the inability to digest protein called gluten that occurs in wheat, oats, rye, and barley. The finding could help millions of people avoid diarrhea, bloating, and other symptoms that occur when they unknowingly eat foods containing gluten. (Source: Crohn's News From Medical News Today)
Pfizer announces plan for stem cell unit
FROM IBD NEWS SERVICES (Source: Investor's Business Daily: HEALTH)
Snp-guided microrna maps (mirmaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways.
We report the results of a disease phenocode analysis interrogating the relationships between structural features and gene expression patterns of disease-linked SNPs, microRNAs and mRNAs of protein-coding genes in association to phenotypes of 16 major human disorders, which was enabled by multiple independent studies of up to 451,012 combined samples including 194,258 disease cases and 256,754 controls. SNP sequence homology-guided microRNA maps (MirMaps) identify consensus components of a disease phenocode consisting of 81 SNPs and 17 microRNAs. microRNAs of the consensus set are associated with at least 4 common human diseases (range 4 to 7 diseases) and manifest sequence homology/complementarity to at least 4 distinct disease-linked SNPs (range 4 to 14 SNPs). Nearly all microRNAs (15 of...
Small molecule p38 map kinase inhibitors for the treatment of inflammatory diseases: novel structures and developments during 2006-2008.
This article reviews the patent and journal publication activities during 2006-2008 describing novel small molecule p38alphainhibitors.
PMID: 18991731 [PubMed - in process] (Source: Current Topics in Medicinal Chemistry)
New information guides available for patients diagnosed with ibd
EFCCA launches new series of guides for the one million people across Europe suffering from inflammatory bowel disease (Source: Nursing in Practice)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Small-intestinal manifestations of dextran sulfate sodium consumption in rats and assessment of the effects of
lactobacillus fermentum
br11
Abstract The dextran sulfate sodium (DSS) colitis model has been utilized to screen for novel therapeutics for ulcerative colitis.
Evidence suggests the small intestine may also be affected by DSS. We characterized the effects of DSS on the small intestine
and assessed the potential for Lactobacillus fermentum BR11 to modify or normalize DSS-induced changes. Rats were allocated to three groups, Water + Vehicle, DSS + Vehicle, and
DSS + L. fermentum BR11. BR11 was administered twice daily for 14 days. DSS (2%) was provided from days 7 to 14. Small-intestinal tissue was
analyzed for sucrase activity, histology, and crypt cell proliferation. Increased ileum crypt depth and cell proliferation
was observed in DSS-treated rats compared to contro...
Results of operative management of crohn?s disease: a series of 50 patients managed by one surgeon
Abstract A computer analysis has been made of clinical experience of Crohn?s disease in Australian patients. Between 1950 and 1978,
50 patients were managed for Crohn?s disease by one of the authors (E.S.R.H.). This group represented 3.1. per cent of 1608
patients treated during the same period for primary inflammatory bowel disease. The mean follow-up period was 8.4 years. Thirty-nine
of the 50 patients were female and 11 male. The small intestine was involved in seven patients, large intestine in 17 and
both small and large intestine in 26. Symptoms were related to the anatomic localization of disease. Four patients have died
(two postoperative deaths and two unrelated to Crohn?s disease). Forty-nine of the 50 patients required operative procedures
and 36 underwent...
Total colectomy, mucosal proctectomy, and ileoanal anastomosis
Abstract A safe and practical procedure for total colectomy and mucosal proctectomy with ileonal anastomosis has been developed and
performed by us on 11 patients with adenomatosis coli and two patients with ulcerative colitis. The major features of the
operative procedure are 1) total removal of the rectal mucosa to just above the dentate line; 2) preservation of anorectal
function by a long rectal cuff procedure achieved by rectal mucosal excision from a level just below the sacral promontory,
using a rectal internal stent and gauze packing techniques for rectal mucosal stripping, with, in some patients, an ileal
reservoir added; and 3) prevention of pelvic sepsis by intraoperative rectal irrigation, rectal cuff drainage, and a temporary
defunctioning loop ileostomy. Of ...
Adalimumab may reduce health-care costs for crohn's disease patients
Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD). IBD occurs most frequently in people in their late teens and twenties. There have been cases in children as young as two years old and in older adults in their seventies and eighties; men and women have an equal chance of getting the disease. (Source: Huliq Health News)
Treatment of choice for acute severe steroid-refractory ulcerative colitis is colectomy
No abstract. (Source: Inflammatory Bowel Diseases)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Azathioprine is superior to budesonide in achieving and maintaining mucosal healing and histologic remission in steroid-dependent crohn's disease
Conclusions: In patients with steroid-dependent inflammatory Crohn's ileocolitis or proximal colitis who achieve clinical remission with conventional steroids, a 1-year treatment with AZA was superior to BUD in achieving and maintaining mucosal healing and histologic remission.(Inflamm Bowel Dis 2008) (Source: Inflammatory Bowel Diseases)
Persistent retention of colitogenic cd4+ memory t cells causes inflammatory bowel diseases to become intractable
Despite the advent of an age when "malignant" leukemia is cured by bone marrow transplantation, "benign" inflammatory bowel diseases (IBDs) are still intractable lifelong diseases. Why is it that once an IBD develops it lasts a long time? We propose that, the same as in the response to vaccination, immune memory T cells that remember the disease are formed in IBDs and, perceiving them as "benign T-cell leukemia"-like lifelong pathology that hematogenously spreads throughout the body, we here propose that the bone marrow itself, which produces large amounts of the survival factor IL-7, is the reservoir for colitogenic CD4+ memory T cells responsible for the intractability of IBDs.(Inflamm Bowel Dis 2008) (Source: Inflammatory Bowel Diseases)
Iron in water supply linked to inflammatory bowel diseases
The risk of developing ulcerative colitis and Crohn's disease is associated with elevated iron levels in drinking water, according to a study in Norway. Reuters Health Information (Source: Medscape PublicHealth Headlines)
Infliximab as a rescue therapy for hospitalized patients with severe ulcerative colitis refractory to systemic corticosteroids
Dig Surg 2008;25:383-386 (DOI:10.1159/000170882) (Source: Digestive Surgery)
Philips' intelligent pill targets drug development and treatment for digestive tract diseases
At this week's opening of the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition (Atlanta, USA, November 16-20, 2008) Philips Research will announce its new intelligent pill technology "iPill", targeted at assisting drug development and enabling new therapies for debilitating and life-threatening digestive tract disorders such as Crohn's disease, colitis and colon cancer. (Source: Crohn's News From Medical News Today)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Fda approves deadly enbrel drug for children
(NaturalNews) An FDA advisory panel has recommended the approval of Amgen's immune-suppressing drug Enbrel (generic name etanercept) for the treatment of psoriasis in children, in spite of ongoing concerns that the drug may have lethal side effects.The recommendation came only two days after an independent panel recommended that the FDA strengthen Enbrel's label with warnings about potentially fatal side effects such as anemia, seizures, serious infections, cancer or neurological problems. It also comes as the FDA is investigating whether the entire drug family of which Enbrel is a part increases the risk of cancer in children, particularly lymphoma.The FDA is investigating 30 reports of cancer in children and young adults who have been treated with drugs in the family, known as tumor necr...
Adalimumab may reduce health-care costs for crohn's disease patients
(American Gastroenterological Association) Inflammatory bowel disease is a term that refers to both ulcerative colitis and Crohn's disease. IBD occurs most frequently in people in their late teens and twenties. There have been cases in children as young as two years old and in older adults in their seventies and eighties; men and women have an equal chance of getting the disease. (Source: EurekAlert! - Medicine and Health)
A common barrier defect for celiac disease and ulcerative colitis.
A Common Barrier Defect for Celiac Disease and Ulcerative Colitis.
Gastroenterology. 2008 Nov 12;
Authors: Mannon PJ
PMID: 19013169 [PubMed - as supplied by publisher] (Source: Gastroenterology)
Withdrawal of immunosuppression in crohn's disease treated with scheduled infliximab maintenance.
Withdrawal of Immunosuppression in Crohn's Disease Treated With Scheduled Infliximab Maintenance.
Gastroenterology. 2008 Nov 12;
Authors: Francis G, Duggan A
PMID: 19013168 [PubMed - as supplied by publisher] (Source: Gastroenterology)
The direct and indirect cost burden of crohn's disease and ulcerative colitis.
Page: 1261DOI: 10.1097/JOM.0b013e318181b8caAuthors: Gibson, Teresa B. PhD; Ng, Eliza MD; Ozminkowski, Ronald J. PhD; Wang, Shaohung PhD; Burton, Wayne N. MD; Goetzel, Ron Z. PhD; Maclean, Ross MD, MBA (Source: Journal of Occupational and Environmental Medicine)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
A short-oligonucleotide microarray that allows improved detection of gastrointestinal tract microbial communities
Conclusions:
In this study we demonstrate the design, testing and application of a highly sensitive, short oligonucleotide community microarray. Our approach allows the rapid discrimination of bacteria inhabiting the human GI tract, at taxonomic levels ranging from species to the superkingdom bacteria. The optimised protocol is available at: http://www.ifr.ac.uk/safety/microarrays/#protocols. It offers a high throughput method for studying the dynamics of the bacterial population over time and between individuals. (Source: BMC Microbiology - Latest articles)
Curcumin attenuates inflammation through inhibition of tlr-4 receptor in experimental colitis.
In this study, we investigated the effects of curcumin on the expression of TLR-4 and MyD88, the upstream signaling pathway in experimental colitis induced in the Sprague-Dawley male rats by intra-rectal administration of trinitrobenzenesulfonic acid (TNBS). The animals which received TNBS were divided into two groups: Group 1, received aqueous suspension of curcumin (100 mg/Kg body weight) 2 h prior to inducing colitis, and the treatment was repeated every day for 5 days, and Group 2 and non-colitis (Group 3) animals received phosphate buffered saline (PBS) in a similar fashion. Non-colitis animals (Group 4) received curcumin and served as controls. Animals were sacrificed on day 5 post-TNBS by cervical dislocation, colon was taken out, and cleaned with PBS. Levels of TLR-4, MyD88, and NF...
Molecular pathogenesis of inflammatory bowel disease: relevance for novel therapies
Personalized Medicine , November 2008, Vol. 5, No. 6, Pages 609-626.
The immense load of microorganisms within the gastrointestinal tract is a great challenge for the mucosal immune system. Whereas the vast majority of commensal bacteria should be tolerated, pathogenic organisms have to be attacked. During inflammatory ... (Source: Future Medicine: Personalized Medicine)
Guidelines for the management of inflammatory bowel disease in children in the united kingdom
These clinical guidelines provide an evidence and consensus based document describing good clinical practice for the investigation and treatment of IBD (ulcerative colitis and crohn's disease) in children under the age of 18 years, which will promote more consistent clinical care. (Source: Gastroenterology and Liver Diseases Specialist Library - Inflammatory bowel disease)
Mesalazine granted us fda approval for ulcerative colitis.
(Source: Inpharma)<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Does the urinary excretion of alpha1-microglobulin and albumin predict clinical disease activity in ulcerative colitis?
CONCLUSION: THE PRESENT STUDY SUGGESTS THAT, AS WITH CRP, URINARY LEVELS OF ALBUMIN AND alpha1-MG INCREASE DURING THE ACTIVE PERIOD OF UC. DURING THE INACTIVE PERIOD, CONCENTRATIONS OF THESE PARAMETERS ARE COMPARABLE TO CONTROLS. THE MEASUREMENT OF alpha1-MG AND/OR MICROALBUMINURIA COULD PROVIDE INFORMATION ON DISEASE SEVERITY AND RESPONSE TO TREATMENT:
PMID: 19002407 [PubMed - as supplied by publisher] (Source: Advances in Therapy)
Mesalazine granted us fda approval for ulcerative colitis.
Page: 23 (Source: Inpharma Weekly)
Abbott's humira® (adalimumab) data shows fistula healing for up to three years in patients with moderate to severe crohn's disease
New data showed that Abbott's (NYSE: ABT) HUMIRA® (adalimumab) provided long-term treatment of fistulas, with more than half of patients with moderate to severe Crohn's disease experiencing fistula healing at three years, according to clinical research presented today at the United European Gastroenterology Week (UEGW) congress in Vienna. (Source: Health News from Medical News Today)
Selected update: mucosal immunology: mismanaged er stress and inflammation
A dysregulated response to endoplasmic reticulum (ER) stress caused by depletion of the transcription factor XBP1 can lead to inflammatory bowel disease. (Source: Nature Signaling Update)
Helminth antigen-based strategy to ameliorate inflammation in an experimental model of colitis
Inflammatory bowel disease (IBD) is the most common and serious chronic inflammatory condition of the gut. Among the distinct T helper (Th) cell subsets, a Th1 type response is associated predominantly with Crohn's disease (CD) while helminth infections generate a strong Th2 type response. IBD is most prevalent in developed countries but rare in countries where infections with helminths are common. Thus, it has been hypothesized that infection with helminth infection influence the development of CD and recent clinical and experimental studies suggest strongly a beneficial role of helminth infection in IBD. In the present study we examined the effects of rectal submucosal administration of helminth antigens on subsequent experimental colitis. Mice were treated with Trichinella spiralis anti...<p> </p><p><b><i>MedWorm Sponsored Message:</i></b> Find out how you can <a href="http://www.medworm.com/rss/medicalsponsorship.php" target="_self">get your message across here</a> by sponsoring this MedWorm news feed.</p>
Caution urged over use of anti-tumour necrosis factor drugs in bowel disease patients
Patients with inflammatory bowel disease should carefully discuss the risks and benefits of anti-tumour-necrosis-factor drugs with their doctors before undergoing treatment with these medications, say researchers. (Source: MedWire News - Consumer Health)
Ask the experts: do sex-related differences affect clinical course and outcome in crohn's disease?
Sunanda V. Kane, MD, MSPH, FACG, discusses gender-related issues that may have an impact on clinical course and/or management in Crohn's disease.
Medscape Gastroenterology (Source: Medscape FamilyMedicine Headlines)
Concomitant carcinoid tumor and papillary urothelial neoplasm of low malignant potential in a patient with crohn's disease: a case report.
Page: 1231DOI: 10.1097/MEG.0b013e328302f484Authors: Owczarek, Danuta a; Cibor, Dorota a; Szczepanski, Wojciech b; Kosowski, Bogdan c; Mach, Tomasz a (Source: European Journal of Gastroenterology & Hepatology)
Fight back against inflammatory bowel disease.
Is it ulcerative colitis or Crohn's disease? These gut-wrenching disorders have much in common, but they also differ significantly. Make sure you can sort them out so you're prepared to intervene appropriately.Page: 34DOI: 10.1097/01.NURSE.0000341077.75953.74Authors: Day, Michael W. RN, CCRN, MSN (Source: Nursing)
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